3B). R526 from the loop among αJ and αI anchors the C-terminal part of the activation loop by forming a salt bridge with E458 at the base of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the key chain https://deaconpfux913431.designertoblog.com/61082978/helping-the-others-realize-the-advantages-of-pkrrating